Part of the General Studies-III question bank for OPSC (OAS) Mains.
A comprehensive, topic-wise practice set of 31 questions on Biotechnology, Nanotechnology & AI for OPSC (OAS) Mains General Studies-III. 16 of them have been set in an actual paper — the years and exams are printed against each (2026, 2025, 2023, 2022, 2021, 2020, 2018, 2017, 2016, 2014, 2022). The rest are practice questions on the same syllabus points.
Previous year questions
| No. | Question | Asked in |
|---|---|---|
| 1 | What is agentic Artificial Intelligence (AI)? Explain its working. Describe its applications with suitable examples. Discuss the advantages, risks and challenges associated with agentic AI systems. | UPSC Mains GS-III 2026 15m,250w |
| 2 | How does nanotechnology offer significant advancements in the field of agriculture? How can this technology help to uplift the socio‑economic status of farmers? | UPSC Mains GS-III 2025 250w |
| 3 | Introduce the concept of Artificial Intelligence (AI). How does AI help clinical diagnosis? Do you perceive any threat to privacy of the individual in the use of AI in healthcare? | UPSC Mains GS-III 2023 150w/10m |
| 4 | Each year a large amount of plant material, cellulose, is deposited on the surface of Planet Earth. What are the natural processes this cellulose undergoes before yielding carbon dioxide, water and other end products? | UPSC Mains GS-III 2022 — |
| 5 | What is the basic principle behind vaccine development? How do vaccines work? What approaches were adopted by the Indian vaccine manufacturers to produce COVID‑19 vaccines? | UPSC Mains GS-III 2022 — |
| 6 | What are the research in developmental achievements in applied biotechnology? How will these achievements help to uplift the poor sections of the society? | UPSC Mains GS-III 2021 250w |
| 7 | The Nobel Prize in Physics of 2014 was jointly awarded to a Akasaki, Amano and Nakamura for the invention of Blue LEDs in1990s. How has this invention impacted the everyday life of human beings? | UPSC Mains GS-III 2021 250w |
| 8 | What do you understand by nanotechnology and how is it helping in health sector? | UPSC Mains GS-III 2020 — |
| 9 | How is science interwoven deeply with our lives? What are the striking changes in agriculture triggered off by the science‑based technologies? | UPSC Mains GS-III 2020 — |
| 10 | COVID‑19 pandemic has caused unprecedented devastation worldwide. However, technological advancements are being availed readily to win over the crisis. Give an account of how technology was sought to aid management to the pandemic. | UPSC Mains GS-III 2020 — |
| 11 | Why is there so much activity in the field of biotechnology in our country? How has this activity benefitted the field of biopharma? | UPSC Mains GS-III 2018 — |
| 12 | Stem cell therapy is gaining popularity in India to treat a wide variety of medical conditions including Leukaemia, Thalassemia, damaged cornea and several burns. Describe briefly what stem cell therapy is and what advantages it has over other treatments? | UPSC Mains GS-III 2017 — |
| 13 | Why is nanotechnology one of the key technologies of the 21st century? Describe the salient features of Indian Government's Mission on Nanoscience and Technology and the scope of its application in the development process of the country. | UPSC Mains GS-III 2016 — |
| 14 | Can overuse and the availability of antibiotics without doctor's prescription, the contributors to the emergence of drug‑resistant diseases in India? What are the available mechanisms for monitoring and control? Critically discuss the various issues involved. | UPSC Mains GS-III 2014 — |
| 15 | Illustrate telemedicine. Describe its purpose and applications. | OPSC OAS Mains 2022 15m,250w – Group B |
Practice questions
| No. | Question | Source |
|---|---|---|
| 16 | Discuss the significance and potential impacts of stem cell technology in the fields of medicine and research. | — |
| 17 | Discussing the significance of the click chemistry, explore its applications in pharmaceutical research and drug discovery. | — |
| 18 | Critically discuss genome analytics as a sunrise opportunity in India? | — |
| 19 | What do you understand by "designer baby". Discuss the potential advantages and threats associated with this concept. | — |
| 20 | How can science and technology combat poverty, inequality, and social exclusion in India? Cite recent initiatives and innovations that have contributed to inclusive growth in the country. | — |
| 21 | Introduce the concept of pharmacogenomics. How can it be applied in the field of infectious disease treatment? | — |
| 22 | GM crops have their own challenges and opportunities associated with commercialization in India. Discuss. | — |
| 23 | What role does biotechnology play in enhancing the livelihoods of farmers and improving agricultural productivity? | — |
| 24 | Discuss the potential issues associated with the use of biotechnology while also exploring the measures implemented by the Indian government to promote its integration into healthcare. | — |
| 25 | Discuss the significance of bio-tissue culture in modern biotechnology. Highlight its applications for advancements in agriculture and medicine. | — |
| 26 | Enumerate the challenges of biopiracy and bioprospecting in India. How can India protect its biodiversity and traditional knowledge from misappropriation by foreign entities? | — |
| 27 | Evaluate merits and demerits of Fixed Dose Combinations (FDCs) in pharmaceuticals. Provide suggestions to enhance the regulatory framework for FDCs in India. | — |
| 28 | How has biotechnology brought about groundbreaking changes in the medical field? Explain. | — |
| 29 | Critically examine the implications of using biometric technology for identification and authentication purposes in India? How can the privacy and security of biometric data be ensured? | — |
| 30 | Why is there so much activity in the field of biotechnology in our country? How has this activity benefited the field of biopharma? | — |
| 31 | Introduce the concept of Artificial Intelligence (AI). How does AI help clinical diagnosis? Do you perceive any threat to privacy of the individual in the use of AI in healthcare? | — |